ABCC4 (Human) Recombinant Protein (Q01)
产品名称: ABCC4 (Human) Recombinant Protein (Q01)
英文名称: ABCC4 (Human) Recombinant Protein (Q01)
产品编号: H00010257-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 邮编 : 11493
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 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human ABCC4 partial ORF ( AAH41560, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
 
- Sequence:
 - MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQP
 
- Theoretical MW (kDa):
 - 37.73
 
- Preparation Method:
 - in vitro wheat germ expression system
 
- Purification:
 - Glutathione Sepharose 4 Fast Flow
 
- Storage Buffer:
 - 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
 
- Storage Instruction:
 - Store at -80°C. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - 12.5% SDS-PAGE Stained with Coomassie Blue.

 
- Note:
 - Best use within three months from the date of receipt of this protein.
 
- MSDS:
 
Download
- Application Image
 
- Enzyme-linked Immunoabsorbent Assay
 
- Western Blot (Recombinant protein)
 
- Antibody Production
 
- Protein Array
 
- Entrez GeneID:
 - 10257
 
- GeneBank Accession#:
 - BC041560
 
- Protein Accession#:
 - AAH41560
 
- Gene Name:
 - ABCC4
 
- Gene Alias:
 - EST170205,MOAT-B,MOATB,MRP4
 
- Gene Description:
 - ATP-binding cassette, sub-family C (CFTR/MRP), member 4
 
- Omim ID:
 - 605250
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq
 
- Other Designations:
 - ATP-binding cassette, sub-family C, member 4,OTTHUMP00000018560,bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4),canalicular multispecific organic anion transporter (ABC superfamily),multidrug resistance-associated protein 4,multispecif
 
- Gene Pathway
 
- Related Disease
 
- Breast cancer
 - Breast Neoplasms
 - Carcinoma
 - Cardiovascular Diseases
 - Colitis, Ulcerative
 - Crohn Disease
 - Diabetes Mellitus, Type 2
 - Drug Toxicity
 - Edema
 - Fanconi Syndrome
 - Genetic Predisposition to Disease
 - HIV Infections
 - Kidney Failure
 - Kidney Failure, Chronic
 - Lung Neoplasms
 - Pulmonary Disease, Chronic Obstructive
 - Tobacco Use Disorder
 - Urinary Bladder Neoplasms
 - Werner syndrome
 
